Research

Selected Mild Traumatic Brain Injury (mTBI) Studies

Behavioral programs incorporating Computer-Assisted Cognitive Rehabilitation are a recommended treatment for traumatic brain injury patients. Behavioral programs are designed to improve function and improve awareness for patients.

Title

Study Design

Review

Clinical Study

Review

Randomized Controlled Trial

Randomized Controlled Trial

Review

Randomized Controlled Trial

Randomized Controlled Trial

Randomized Controlled Trial

Randomized Controlled Trial

Evaluation Study

Randomized Controlled Trial

Selected Fear Avoidance Beliefs Training (FABT) Studies

Fear Avoidance Beliefs are associated with disability, reduced function, and impairment in chronic pain patients. FABT has demonstrated improvements in disability, function, impairment, and return to work in chronic pain patients.

Randomized Controlled Trial

Fear Avoidance Beliefs Training improves disability and pain intensity in patient’s low back pain

Randomized Controlled Trial

Fear Avoidance Beliefs Training significantly improved work related fear avoidance beliefs in workers with chronic pain

Comparative Study

Patients with high fear avoidance benefit from functional rehabilitation programs that include Fear Avoidance Beliefs Training

Randomized Controlled Trial

Chronic low back pain patients with reduced function demonstrated superior benefits over treatment as usual on function, fear, and pain

Randomized Controlled Trial

Function in chronic pain patients is significantly reduced in patients with high Fear Avoidance Beliefs

Randomized Controlled Trial

Function in chronic pain patients is significantly reduced in patients with high Fear Avoidance Beliefs

Exploratory Study

Early Fear Avoidance Training prevents the onset of chronic pain

Randomized Controlled Trial

Therapeutic patient education

Research Pipeline

Georgia State University

Validation and feasibility of KarunaHOME for use in physical therapy

Ongoing, actively recruiting

Dr. Sujay Galen, PhD

Chair, Department of Physical Therapy, Georgia State University

Penn Medicine

A randomized controlled trial on patients with chronic low back pain

Ongoing, actively recruiting

Dr. Michael Ashburn, MD, MPH, MBA

Director, Pain Medicine and Palliative Care Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania

Karuna Labs

A randomized controlled trial on KarunaHOME for patients with general chronic shoulder pain

Ongoing, actively recruiting

Dr. Michael Trujillo, PhD

VP of Clinical Affairs, Karuna Labs

UCSF

Inpatient Trial: PRISM (Pain Relief with Individualized brain Stimulation)

Ongoing, actively recruiting

Dr. Prasad Shirvalkar, MD, PhD

Neurologist and Pain Medicine Specialist UCSF Dept. of Anesthesia

Validating biomarkers of chronic pain and digital therapeutics

Santa Clara University

Pending

Julia A. Scott, PhD

Senior Research Associate BioInnovation and Design Lab, Santa Clara University

Description

Title

Design

High fear avoidance beliefs is associated with sustained impairments in returning to work in chronic pain patients

Randomized Controlled Trial

PI

Institution

Design

Status